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TGF- is a cytokine exerting immunosuppressive functions in the TME (112) and it was shown to modulate the expression of CD16 and thus the NK cell cytotoxic potential (113)

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Taubert D, Rosenkranz A, Berkels R, Roesen R, Schomig E (2004) Acute effects of glucose and insulin on vascular endothelium