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The duration depends on individual goals and response, typically ranging from several months to ongoing use

As mentioned, GLP-1RAs can reduce the content of systemic inflammation markers

Tirzepatides imbalanced receptor engagement, which favors GIP receptor activation, combined with biased signaling at the GLP-1 receptor, further enhances insulin secretion and metabolic benefits (35, 36)

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Clinical trials are also essential to evaluate the safety, tolerability, and potential synergistic effects of GLP-1RAs in the context of cancer pain management