Taking your GLP-1 injection at the same time every week (or every day, for daily formulations) matters more than choosing the theoretically perfect hour
Expected outcomes: Slower visual field loss, potentially 30-50% better preservation versus pressure control alone based on small trials
Indeed, it was demonstrated that heterodimerization of 1-cysPrx with GSH-saturated GSTP results in S -glutathionylation of the oxidized cysteine in 1-cysPrx followed by subsequent spontaneous reduction of the mixed disulfide and restoration of enzymatic activity (Manevich et al., 2004)
Despite normalization of plasma homocysteine concentration, administration of folic acid, vitamin B 6 , and vitamin B 12 for 6 months was insufficient to restore normal vascular function in monkeys maintained for 17 months on an atherosclerotic diet that produced both hypercholesterolemia and hyperhomocysteinemia (Lentz et al, 1997)
GSH also exerts negative feedback inhibition on GCL, meaning the cell self-regulates its own production