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A previous study demonstrated that in ASS1-deficient myxofibrosarcoma, ASS1 re-expression inhibited tumor growth by inhibiting tumor angiogenesis and inducing G1 phase arrest, indicating that ASS1 was a new tumor suppressor (Huang et al., 2013)

however, it posits a regulatory mechanism where TIMPs modulate the activity of MMPs, thereby balancing extracellular matrix degradation and formation

Table 2 Prospective studies that analyzed thyroid function in COVID-19 patients during admission

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Importantly, this burning sensation is not a sign of an allergic reaction or dangerous side effectit is a common, self-limiting response to the injection itself