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10.1016/j.neuron.2006.07.005 93

The starting dose is 0.25 milligrams for 4 weeks before increasing the dosage to 0.5 milligrams

Non-surgical treatments such as radiofrequency microneedling are effective for mild to moderate skin laxity but cannot replace surgery for patients with significant excess skin

Oxidative stress caused by the overproduction of ROS and reactive nitrogen species, as well as changes in antioxidant enzyme activities, is implicated in NEO-induced injury to cellular molecules such as lipids, DNA, and proteins (Wang et al