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The gradual onset is actually beneficial because it supports sustainable lifestyle changes rather than rapid or extreme shifts in eating behavior

But this remains theoretical until clinical data emerges

ONeil noted that research consistently shows that most patients regain a significant amount of their weight once medication treatment stops

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471 The mechanisms by which SGLT2 inhibitors treat heart failure include lowering blood glucose levels by inhibiting the SGLT2 protein in the renal tubules and reducing glucose reabsorption in the tubules