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They have been shown to reduce sympathetic outflow, enhance myocardial glucose uptake, and improve left ventricular function [7]

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GLP-1 receptor activation in the spinal cord and brainstem may be anti-inflammatory and pain-relieving, while effects on peripheral sensory neurons may, under certain conditions, produce sensitization

Generally, single use will not lead to hypoglycemia, but if combined with sulfonylureas or insulin, attention should be paid to prevent hypoglycemia (142)

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