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doi: 10.1016/j.physbeh.2015.06.001, 53

Injectable protocols reach 10 to 20x the tissue concentration of topical application

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This threshold is supported by volunteer studies using semaglutide, where residual solids were detected on ultrasound despite 8 h fasting [7], and by matched-pair data showing a five-fold rise in endoscopic residue among GLP-1RA users 7