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A Critique of Calorie Counting for Weight Loss: The Science Behind Calorie Deficits

And insurance companies (including Medicare), were only covering GLP-1s for specific indications that didnt include wanting to look skinny on Zoom calls

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PE-22-28 Safety Considerations# PE-22-28's safety profile is less burdened by mechanism-specific concerns: TREK-1 channels are expressed throughout the body (brain, heart, vasculature, gastrointestinal tract), so systemic TREK-1 blockade could theoretically affect cardiovascular function, pain sensation, and gastrointestinal motility

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