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Review: Advances in GLP-1 receptor agonists delivery systems for obesity and diabetes A new review article published in the journal Acta Pharmaceutica Sinica B summarizes advancements in drug delivery systems for three main glucagon-like peptide-1 receptor agonists (GLP-1RAs), which are recommended for selected patients with obesity or type 2 diabetes, depending on indication, comorbidities, and treatment goals

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For example, proinflammatory cytokines such as IL-1 have been shown to impair neurotransmitter homeostasis (e.g., decreased serotonin levels and enhanced glutamatergic excitotoxicity), induce oxidative stress (OS) and neuronal pyroptosis, and lead to mitochondrial dysfunction and synaptic protein lossultimately fostering a bidirectional relationship between epilepsy and depression (Zhu et al., 2006

For many veterans, managing chronic health conditions like type 2 diabetes or navigating long-term weight management is a daily reality