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Its staking its future on the drugs, with plans to continue selling compounded GLP-1s even when shortages of the versions approved by regulators come to an end a strategy that policy experts say could land the company in court

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The two medications are cleared by entirely different routes: hydroxyzine is metabolized by liver cytochrome P450 enzymes (CYP3A4 and CYP2D6), while semaglutide is a peptide broken down by proteolytic cleavage and fatty-acid beta-oxidation

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Pharmacokinetic profile Retatrutide exhibits a favourable pharmacokinetic profile, with a half-life of approximately 6 days, allowing for convenient once-weekly administration