5-Amino-1MQ is an Nicotinamide N-methyltransferase (NNMT) inhibitor that has been shown to reverse diet-induced obesity
If you are pregnant, breastfeeding, or have specific medical concernssuch as kidney disease, low potassium levels, or certain blood disordersplease mention these during your consultation
Studies, including those published as recently as late 2025, indicate that this mechanism can lead to a reduction in fat cell size and proliferation, alongside an increase in resting metabolic rate
If you're on a plant-based diet or don't eat fortified foods containing B12, supplementation can be a simple, effective way to get vitamin B12 and support your weight loss goals while on Ozempic therapy
By blocking NNMT activity, the compound preserves nicotinamide availability for the NAD+ salvage pathway, leading to 1.2- to 1.6-fold increases in intracellular NAD+ concentrations