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Description

More receptors means more weight loss: 28.7% for retatrutide vs 22.5% for tirzepatide in trials, but also more side effects

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This suggests a need for further investigation

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OW, once-weekly dosing

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Whats more, the studies of brodalumab, a humanized monoclonal antibody that binds to IL-17RA, was stopped because of the relative lack of efficacy in the initial asthma clinical trial and a questionable safety issue (58)

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