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Typically, people with a personal or family history of certain types of thyroid cancer, those with a history of pancreatitis or gastroparesis, and those who are pregnant or planning to be should not take these medications

Heavier individuals also tend to tolerate escalation steps more smoothly because the per-kilogram exposure at each dose level is lower

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Some users also experience mild anxiety about the new medication or excitement about early weight loss that interferes with the mental relaxation needed for sleep

It fundamentally alters how your body manages energy, stores fat, and responds to food intake