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The effect builds up and is more pronounced the longer treatment is continued

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Not only that, the integrated probiotic expressing IL-15 (Bac) and pH-sensitive lysozyme nanoparticles (LYC) LYC@Bac can activate the mTOR pathway in NK cells, upregulate NKG2D to activate NK cells, and enhance granzyme and perforin secretion to strengthen cancer immunotherapy (238)