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Moreover, we assist them with identifying a safe starting dose for the first-in-human clinical trial and the creation of the pharmacokinetic design for the human ascending dose trial
Nat Commun 11:498 Lee YZ, Yang CW, Chang HY et al (2014) Discovery of selective inhibitors of glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells
Produced under controlled conditions, it is intended for analytical and laboratory research involving NNMT-related metabolic pathway studies
The expression level and activity of SP1 are often abnormally elevated in lung cancer tissues, and its high expression is significantly associated with a poor prognosis ( 2.7.2 Naamidine J inhibits the nuclear translocation of SP1 by targeting CSE1L to slow down lung injury Naamidine J (NJ) is a marine alkaloid and has been identified as a specific inhibitor of the nuclear transport protein CSE1L through chemical proteomics technology
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