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Research and clinical investigation have produced one of the most extensively characterised profiles of any dual incretin research compound available in Europe: The SURPASS-2 trial documented Tirzepatides superiority over Semaglutide 1mg across HbA1c reduction and body weight loss providing the first head-to-head clinical validation that dual GIPR and GLP-1R co-agonism produces superior metabolic outcomes to the best-in-class selective GLP-1R monoagonist, establishing Tirzepatide as the new efficacy benchmark in incretin pharmacology and generating significant research interest across EU institutions in the mechanistic basis of dual incretin superiority

Side effects at 12mg affect approximately 28% of users with nausea and 24% with digestive changes

Dig Dis Sci 50:13721375

J., Billah, B

Faster, more noticeable results : The higher-intensity GH response generally translates to more visible changes in body composition within the first few months