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Helping regenerate tissue and reducing inflammation may promote a healthier environment for regrowth and less shedding
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Orforglipron has demonstrated meaningful HbA1c reductions in the ATTAIN-2 trial, which included patients with type 2 diabetes
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The timepoint chosen (when drug-tolerant cells are emerging after treatment) probably contributes to this effect, and later timepoints (when cells perhaps enter senescence or other more terminally arrested states) are more likely to reflect the expected gene expression patterns
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