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Phase 1/2 Study of the CD56-Targeting antibody-drug conjugate lorvotuzumab mertansine (imgn901) in combination with carboplatin/etoposide in small-cell lung cancer patients with extensive-stage disease

NAC and GSH exhibited pro-oncogenetic effects on human HCC cells and desensitized NRF2/GCLC related antioxidant production pathway in vitro Since we observed that antioxidants promoted tumorigenesis and growth in mouse spontaneous HCC and xenograft models, we wished to confirm whether these promoting effects also existed in human HCC cells both in vitro and in vivo

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6 , e13852 (2018)