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Slow and gradual dose adjustments are key for this group, as they help reduce the risk of gastrointestinal side effects like nausea and vomiting, which could lead to volume depletion

(b) consecutive treatments with NFT (including intermittent washout phases) exhibited an additive effect with respect to the increase in glutathione levels

Glycaemic efficacy, including hypoglycaemia and hyperglycaemia, should be evaluated with measurement of blood glucose level and HbA 1c at three months, especially if the doses of other antihyperglycaemic agents were reduced or ceased

Tirzepatide, approved by the FDA and available as Zepbound, acts on GLP-1 and GIP receptors whereas Retatrutide includes an additional action on GCG receptors, offering potential for greater weight loss as noted in clinical trials

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