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The risk of vitiligo worsening is much higher in individuals with permanent vitiligo, as the disease may be aggravated by exposure to depigmenting agents

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, Bruemmer, D

2 GLP-1RAs taken once weekly may take four to five weeks to achieve steady state, while clinical effectiveness may be longer depending on many factors such as age, sex, body weight, and liver and kidney function

However, the authors raised concerns regarding maternal nutrient depletion due to rapid weight loss, which could potentially impact milk production and composition