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Cats with chronic kidney disease have been shown to exhibit significantly lower reduced glutathione (GSH) and GSH to GSSG ratio and significantly higher GSSG compared with clinically normal, age-matched cats (Reference Piyarungsri and Pusoonthornthum26)

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Whatever share of the flux calls on GSH, DHA-dependent changes in the status of glutathione and related molecules such as S -nitrosoglutathione (GSNO) might be detected by the cell as a readout of increased oxidative load (Lindermayr 2018

For instance, stranguria is a common urologic disease that is considered to cause by excessive damp heat in the lower energizer

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