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Obviously, if there's any sort of vagal nerve dysfunction, you're stuck in this dysautonomic sympathetic driven state

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CagriSema is an investigational weight loss injection combining semaglutide 2.4 mg (a GLP-1 agonist, the drug in Wegovy) and cagrilintide 2.4 mg (an amylin analogue)

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Its much less potent than GLP-1s, but the muscle-sparing effect is important, as one-third of the weight lost on GLP-1s is muscle mass

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