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Official Injection Sites for GLP-1 Medications According to their FDA-approved prescribing information, GLP-1 medications semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound) are administered as injections just under the skin (subcutaneous) in three areas: Abdomen avoid the 2 inches (5 cm) directly around the navel Thigh outer/front thigh Upper arm back of the upper arm All four FDA labels (Ozempic 1 , Zepbound 2 , Mounjaro 3 , Wegovy 4 ) explicitly state that patients should rotate injection sites with each dose
If youve been using compounded GLP-1 medications and are planning pregnancy, its especially important to document exactly what youve been taking (including the specific formulation, concentration, and dose) so your healthcare provider has complete information
Risks Nausea, vomiting, constipation, and diarrhea are the most common side effects, but they tend to improve with time
The Meteoric Rise of GLP-1 Utilization The impact of GLP-1s on Medicare spending is already remarkable
The oral contraceptive may not get absorbed properly due to the GLP-1 causing slow emptying of the stomach
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