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These results suggest that inhibition of Gpx activity inhibits Con A-induced T-cell activation and proliferation through continued ROS-induced T-cell hyporesponsiveness

doi: 10.1097/HEP.0000000000000971

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Given that Ex9 is a GLP-1 antagonist and thus requires intact ligand, we expected that it would have no impact on Gcg RA Null mice that do not produce GLP-1 (Fig