doi: 10.9734/ijecc/2023/v13i82149 90 SeixasP
Unlike ulcerative colitis, which is limited to the colonic mucosa, Crohns disease features skip lesions areas of diseased bowel separated by segments of normal-appearing tissue and may involve multiple layers of the intestinal wall, leading to fibrosis, stricture formation, and fistulization, as described by the Crohns & Colitis Foundation
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These effects often improve over time with proper dose adjustments
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