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Furthermore, transgenic Drosophila models expressing human AD-associated genes, such as amyloid-beta (A) and tau, have enabled precise exploration of disease progression and therapeutic interventions (Table 13)

NTS prepared as previously described and cultured in M199 supplemented with 5.5 mM D-glucose, penicillin-streptomycin and 5% heat inactivated fetal bovine serum were incubated at 37 C in a clear bottom flat well plate in a 5% CO 2 incubator overnight

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