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Semaglutide weight loss: What you need to know
According to PubMed, recent comprehensive reviews document effects on cardiovascular protection (reduced major adverse cardiovascular events), neuroprotection (reduced neuroinflammation, potential effects on Alzheimer's pathology), renal protection (reduced albuminuria and renal decline), hepatic improvement (reduced steatosis and fibrosis markers), adipose tissue remodeling (enhanced mitochondrial biogenesis, beige adipocyte programming, reduced visceral fat inflammation), modulation of gut microbiota composition, and even preliminary signals in obstructive sleep apnoea, substance use disorders, and tumour biology (Lu et al., 2024, DOI
They found that people taking Mounjaro lost an average of 15% of their body weight after 72 weeks, with some people losing as high as 20% with higher doses (50-55% of people taking Mounjaro)
It sounds like something straight out of high school chemistry class
(By contrast, less than 4% of people who were taking Ozempic without insulin experienced low blood sugar.) In clinical trials of Wegovy , just over 6% of people experienced hypoglycemianearly three times as many as those taking a placebo
