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Intrinsic sympathomimetic activity

[5] While the precise mechanisms of action for NAD+ therapys purported benefits are not fully elucidated, multiple lines of research suggest several contributing effects

A major cause of this is a slowing metabolism, which prevents your body from quickly and effectively breaking down fat to use as a source of energy

This makes supplements more similar to the natural kind of B12 in foods and a combination of methylcobalamin, adenosylcobalamin and hydroxocobalamin is considered ideal