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2024;99 doi: 10.1016/j.jclinane.2024.111668

Unraveling the IGF system interactome in sarcomas exploits novel therapeutic options

However, in the absence of evidence for cysteinylation of KEAP1 in cells, we cannot completely exclude the possibility that Cys signaling is mediated indirectly

Metformin's primary mechanism involves activation of AMP-activated protein kinase (AMPK) in hepatocytes, which suppresses gluconeogenesis and significantly reduces hepatic glucose output