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Intriguingly, a significant increase in total and selenium-dependent GPx ratios was observed ( P = 0.0099 and P = 0.0096, respectively) (Figures 6D and E), indicating an adaptive upregulation to mitigate oxidative damage, while the non-selenium-dependent GPx ratio remained stable (Figure 6F)

Failure to clear senescent cells also lead to a pro-tumorigenic microenvironment characterized by chronic inflammation because of the SASP 12,25

Clade 2 GS-like genes exhibit up-regulation predominantly in pre/non-parasitic stages, while Clade 3 GS-like genes are highly up-regulated, and often specifically expressed, during the plant-parasitic stages of endoparasitism

Updated June 20, 2024

Diabetes Care 39 , 596602 (2016)