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9 Nrf2 is usually locked in the cytoplasm, but activation by DMF/MMF allows it to translocate to the nucleus where it activates a pathway of genes involved in antioxidant responses, detoxification, and the activity of cytoprotective anti-inflammatory factors

doi:10.1007/s13300-018-0535-9

GSH is also involved in the neutralization of lipid aldehydes (4-HNE, MDA) generated by mitochondrial lipid peroxidation