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Second, despite employing sensitivity analyses, disproportionality metrics carry inherent false-positive risks that require confirmation through controlled studies 76

c ) Western blots showing BRD4 degradation in WT or WDR26-KO HEK293T cells treated with the indicated concentration of ZZ1 for 5 h

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To quantify these effects, we measured the mean GFP-fluorescence intensity at the ONM and nearby cytosol, and used their ratio to determine the relative ONM content of the Nt 7 constructs