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doi:10.1021/bi2009322 [ACS] 109

For a conversational take, imagine desire as a muscle: it weakens without use, but with the right exercises and support, it can strengthen again

8 In muscle insulin resistance, glucose transport into the cell is impaired

Each ingredient works through a different pathway smooth muscle relaxation (papaverine), sympathetic blockade (phentolamine), and direct vasodilation with cGMP stimulation (prostaglandin E1)