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If a patient is severely deficient, a physician might recommend an injection every other day or daily for the first week to rapidly saturate the bodys tissues

10.1002/alz.12482 Alzheimers Dement

These are not small studies

Vitamin B6 helps the pancreas produce enzymes that aid indigestion

In a study by Elovaris et al., intraduodenal administration of l-valine at moderate and at supraphysiological doses to healthy young men had no effect on energy intake or blood glucose regulation, suggesting that l-valine does not have important glucoregulatory or appetite-suppressant effects in humans [39]