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Adverse effects of incretin mimetics Potential adverse effects of incretin mimetics include: Hypoglycemia when taken with insulin GI distress Pancreatitis Renal insufficiency Possible risk of thyroid cancer Other non-insulin, injectable diabetes medications GIP/GLP-1 receptor co-agonists GIP/GLP-1 receptor co-agonists are used to treat type 2 diabetes only

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Decreased sleep can also increase cortisol the stress hormone leading to increased fat

Cardiovascular protection: arterial inflammation drives plaque formation and rupture

The available data and in particularly those in human studies show a very low rate of fermentation (if at all) with little SCFA production and thus a very low caloric yield