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This gain was believed to stem from the hunger-inducing effect of ghrelin receptor stimulation [18]

Plain sterile water, while suitable for immediate use, offers no such preservative effect, making the reconstituted solution much more vulnerable to bacterial proliferation and thus shortening its viable lifespan significantly

however, it does not have the vasodilatory, hypolipidemic, and gastrointestinal upset

The molecular mechanism underlying lactate-induced downregulation of ACSL4 via MCT1 remains incompletely elucidated, although accumulating evidence suggests a potential involvement of the lactate-induced STAT3 signaling pathway (197,198)

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