For my patients, I always begin with foundational pillars: Nutrition: nutrient-dense, anti-inflammatory eating with adequate protein
Consider L-Glutathione if you want skin-brightening, anti-aging, and detox benefits, and L-Glutamine if you wish to improve skin from within- good gut health, better muscle recovery, immune resilience, and quick healing
5 ArboixA.ComesE.Garca-ErolesL.MassonsJ.OliveresM.BalcellsM.et al (2002)
The only published dosing protocol is from mouse studies: 5 mg/kg by intraperitoneal injection, given intermittently over weeks
Scenario 2 (delayed or limited approval): If cardiovascular safety concerns emerge (glucagon agonism theoretically increases heart rate and may elevate blood pressure in susceptible individuals) or gastrointestinal tolerability limits real-world adherence, retatrutide remains investigational