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doi: 10.1016/S1474-4422(23)00378-2

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The expression of several GSTFs including GSTF7 and a GSTL gene were also markedly up-regulated after the fungal inoculation (Figure 2A)

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El ensayo OASIS 1, en personas con obesidad y sobrepeso sin DM2, evidenci que la SEMA oral a 50 mg logr una prdida media del 15,1% del peso corporal frente al 2,4% con placebo en 68 semanas, aunque con una incidencia relevante de efectos gastrointestinales y disestesias en el 13% de participantes, lo que ha impulsado el estudio de dosis intermedias para optimizar eficacia y tolerabilidad