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Synthesis and structural characterization of soluble neuromelanin analogs provides important clues to its biosynthesis

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The higher level of GSSG observed in the serum of many children with autism spectrum disorders [4648, 50, 85, 87, 91] is likely to truly reflect increased oxidative stress as there is no significant difference in GPx-1 activity in serum or platelets [63, 84] and GPx-1 is significantly lower in the erythrocytes of children with autistic disorder compared to controls

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The approach adds complexity but extends useful product life for users with lower consumption rates