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The ulcerative variant of IC/PBS is characterized by a more significant presence of MCs, elevated levels of histamine, and increased production of nitric oxide synthase (NOS) compared to the non-ulcerative form (Logadottir et al., 2013)

Actually, many of these medicines were originally made for diabetes

However, no pharmaceutical company played any role in the scientific content of the present article, which has been written independently and reflects only the opinions of the authors, without no imput from the pharmaceutical industry

Treatment of diabetic kidney disease: current and future