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[1] [2] Key findings included: Participants receiving the highest dose (12 mg) achieved a mean weight reduction of approximately 17.5% of body weight at 24 weeks

In the SURMOUNT-1 trial, approximately 9% of participants on the highest 15mg dose did not achieve clinically meaningful weight loss of 5% or more

The study further shows that extended treatment duration elicits robust anti-fibrotic effects, consistent with the primary outcomes of the ESSENCE Phase 3 clinical trial, and recapitulates circulating biomarker signatures observed in semaglutide-treated MASH patients

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