The five most common include: Vascular issues
Bioavailability of dietary polyphenols and gut microbiota metabolism: antimicrobial properties
The traditional signs of apoptosis, such as mitochondrial cytochrome c release, caspase activation, and chromatin breakage, are notably absent in these dead cells [23, 24]
It causes an immediate release of almost all the granules (containing serotonin, histamine, chemokines, cytokines, enzymes, heparin, and prostaglandins), which trigger itching, swelling, mucous, and anaphylaxis.[ref] A delayed response by mast cells comes from the formation of other mediators, such as prostaglandin D2
Some are far safer than others, but its a sprawling and complicated picture to paint