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A study conducted on an animal model revealed that similarly to vitamin D, the benefits of selenium supplementation are largely influenced by baseline selenium concentration (250)

Approved health claims: Vitamin B12 contributes to normal energy-yielding metabolism and reduction of tiredness and fatigue, Vitamin B12 contributes to the reduction of tiredness and fatigue Calcium contributes to normal muscle function, Calcium contributes to normal energy-yielding metabolism Calcium Alpha-Ketoglutarate (Ca-AKG) Rejuvenation study in humans showed reduced biological aging markers over 7 months Study L-Carnitine Meta-analysis shows benefits for physical performance and recovery Study Coenzyme Q10 (Ubiquinone) Shown to support mitochondrial function and reduce fatigue Study These ingredients are studied individually but their combined effect lies in how they support the same energy system

doi:10.1007/s11427-016-5083-9 29

Follow all recommendations given to you by your provider so that your customized vitamin treatment is as effective as possible

Suggests meaningful reductions in hard outcomes (HF hospitalization & mortality) in HFpEF with obesity + T2D, not just symptom relief