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Studies focus on receptor binding affinity, activation kinetics, and phosphorylation mechanisms associated with receptor engagement

Only one subject required restarting replacement therapy with hemodialysis during follow-up, but it was not considered to be related to the drug

Lysates were centrifuged at 7,000 g for 10 min by MX-100 (Tomy Seiko, Tokyo, Japan), and the supernatant was applied to GST Spin Trap column (GE Healthcare Life Sciences) and kept it for 10 min at room temperature

The time delay is due to the reduction of oxidative stress & pigment reduction internally

The second most common complaint category