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In contrast to the effects on IGF1R signaling, however, co-incubation of these cells with either sc- or dcLCDV1-VILP at concentrations from 0.1 to 1000 nM had no significant effect on phosphorylation on insulin stimulation of IR Y1150/Y1151 or its downstream kinases (Fig

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130.8 mmHg) compared to those in the higher glucose disposal rate group (greater than 7.9 mg/kg/bw) (p = 0.0072) while the difference in diastolic blood pressure was not statistically significant (p = 0.1255)

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