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Injection-site reactions are among the most commonly reported side effects: patients may experience pain, stinging, or mild burning at the IM injection site

Rotate injection sites weekly (abdomen, thighs, upper arms) to reduce local irritation [10]

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When osteosarcoma cells were treated with -rays and agave, the cell viability was more inhibited than those treated with single radiation, which indicated that agave effectively improves the killing effect of radiotherapy in osteosarcoma cells (Table 1)

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