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The argument is not that a single early appointment is a strain, but that the precedent of making such exceptions could be

doi: 10.3892/ijo.23.5.1317 117 ShimakuraSBolandCR

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While specific therapies for IBM are still lacking, NAD + boosters have shown promising results in various models, including nematodes with amyloid aggregation, aged rodents, and human muscle cells from IBM patients