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The compound has been characterized in rat and mouse cognitive-research models principally scopolamine-induced cognitive impairment, aged-rat cognitive decline, and the APP/PS1 transgenic Alzheimers disease model with reported effects on hippocampal synaptogenesis, dendritic spine density, and Morris water maze performance

10.14336/AD.2019.0508 Aging Dis

Patel concurs and adds that every once in a while people who use his low-dosage (100 or 175 milligrams) topical treatment will experience a minor rash that quickly dissipates. These individuals should lower the dose to better suit their needs, he advises