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In recent years, there have been many studies emphasizing the importance of WRN in DNA metabolism, cancer, and aging (Peng et al

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Frequency Standard use is once daily, though some regimens may recommend twice-daily applications

Fixed sections were washed in PBS, permeabilized with 0.3% Nonidet P-40 for 5 min, and blocked with 2.5% normal goat serum (NGS) for 1 hour